Grand Shrine at Ise
Refers specifically to the Ise Grand Shrine (伊勢神宮), the most important Shinto shrine in Japan. Often used in formal or religious contexts.
大神宮は伊勢市にある。
The Grand Shrine is in Ise City.
多くの人が大神宮に参拝する。
Many people visit the Grand Shrine to worship.