rude; presumptuous; cheeky; outspoken
Describes behavior or speech that lacks restraint or consideration for others, often crossing social boundaries. Can range from mild cheekiness to outright rudeness.
彼の無遠慮な発言に、みんな驚いた。
Everyone was surprised by his rude remark.
無遠慮に人の家に上がり込むのはやめてください。
Please don't barge into someone's house without consideration.
He kept firing off blunt, presumptuous questions.
She looked around someone else's room without any restraint.
He's a newcomer, yet he acts so presumptuously that it's a real problem.
I was taken aback by how presumptuous he was.
無遠慮 emphasizes brazen, tactless behavior without restraint, whereas 無神経 more broadly describes failing to notice or care about others' feelings.