expression, ichidan verb
give up as hopeless; wash one's hands of
Used when one decides to abandon a person, plan, or situation after judging it to be futile or beyond help. Often implies a final, resigned decision.
彼は何度も失敗した事業に見切りを付けた。
He gave up on the business that had failed many times.
あの政治家
You'd better wash your hands of that politician.