i-adjective
Often used in a somewhat literary or formal context. Can carry a nuance of being shrewd or discerning, but not necessarily negative.
彼は賢しい判断で難局を乗り切った。
He navigated the difficult situation with a wise decision.
i-adjective
smart-alecky; cheeky; impertinent
Used to describe someone who is overly clever in an irritating or presumptuous way, often with a nuance of being too big for one's britches.
あの子は賢しい口をきく。
That kid talks back cheekily.
賢しい真似をするな。
Don't get smart with me.