Usage patterns
〈組織〉の主軸となるto become the core/pillar of an organization or team
He has become the core player of the team.
〈事〉を主軸に据えるto make something the central focus of a plan or policy
The company has made the new technology its central focus.
〈人〉が主軸を担うfor someone to take on the central, leading role
She is taking on the leading role in the project.
主軸として活躍するto be active/prominent as the key figure
He played an active role as the key player of the team.
主軸が回転するfor the main shaft/spindle to rotate
The engine's main shaft rotates at high speed.