expression
there is nothing more that can be done; it's all over
A set phrase used when a situation has reached a dead end and no further action is possible. Often carries a nuance of resignation or finality.
ここまで来たら万事休すだ。
At this point, there is nothing more we can do.
資金が底をつき、万事休すとなった。
We ran out of funds, and that was the end of it.