Usage patterns
事務をするto do office/clerical work
She does office work at a company.
事務に追われるto be swamped with office work
At the end of the month I'm always swamped with office work.
事務を担当するto be in charge of office/administrative work
The new employee ended up being in charge of the office work.
Expressions
事務を執るattend to business; handle office work 事務を見るattend to business; handle office work