General physical or mental weariness. Often used in set phrases like 疲れが出る or 疲れを取る.
The tiredness from work caught up with me, so I went to bed early.
I relieved the fatigue from the trip at the hot spring.
After coming back from the trip, the fatigue suddenly hit me.
With all the overtime, my fatigue has been building up.
Lately I've often been feeling fatigue in my body.
Even though I slept well, I still can't shake off the fatigue.
travel fatigue; weariness from a journey