Usage patterns
疲れが出るfor fatigue to catch up with one; to start feeling tired
After coming back from the trip, the fatigue suddenly hit me.
疲れがたまるfor fatigue to accumulate; to become worn down over time
With all the overtime, my fatigue has been building up.
疲れを感じるto feel tired; to sense one's own fatigue
Lately I've often been feeling fatigue in my body.
疲れが取れないfor fatigue not to go away; to still feel worn out
Even though I slept well, I still can't shake off the fatigue.
Expressions
疲れを取るrelieve fatigue; recover from tiredness お疲れサマンサthank you for your hard work; good work