Usage patterns
〈場所〉を行き先にするto make somewhere one's destination
For this trip, we made Hokkaido our destination.
行き先が分からないnot to know where someone or something has gone
The dog ran away, and I don't know where it went.
行き先が不安だto feel uneasy about one's future prospects
I'm uneasy about where the company is headed.
行き先を告げるto tell someone one's destination
I told the taxi driver my destination.