Usage patterns
〈動物〉が巣を作るfor an animal to build a nest
A small bird built a nest in the garden tree.
〈動物〉が巣を張るfor a spider to spin a web
A spider has spun a web under the eaves.
〈場所〉が〈人〉の巣になるfor a place to become someone's hideout or hangout
That abandoned house had become a hangout for delinquents.
〈動物〉が巣を離れるfor a young animal to leave the nest
The time will come for the young bird to leave the nest.
Expressions
蜂の巣beehive; hive; honeycomb · full of holes; Swiss cheese · beef reticulum; honeycomb tripe · swage block