If you walk using that tall building as a landmark, you'll reach the station.
An objective or target one has in mind; often used with verbs like する, 探す, 来る, etc.
彼はお金を目当てにその仕事を始めた。
He started that job with the aim of making money.
観光客はお土産を目当てにその店に来る。
Tourists come to that shop looking for souvenirs.
A device on a gun used for aiming; a technical term.
See also: 照準器
ライフルの目当てを調整する。
Adjust the sight on the rifle.
I walked toward that tall tower, using it as a landmark.
I lined up before the store opened, hoping to catch the sale.
He's dating her just for her money.
I didn't come here with any particular goal in mind.