I was nervous at first, but I soon got used to it.
The first train is at 5 a.m.
He came first.
First, please wash your hands.
Could you explain it from the very beginning?
I was nervous at first, but I got used to it quickly.
最初 is the general, neutral word for 'the first time' or 'the beginning' of anything, while 手始め specifically points to a deliberate first step taken to start an activity.
最初 simply means 'first' in order, whereas 皮切り implies that a chain of related events follows the first one.
最初 is a general word for 'the first/beginning' of anything, while 初回 specifically refers to the first installment or round of a recurring series or event.
最初 simply means 'first' in a temporal or sequential sense, whereas 真っ先 emphasizes acting or standing before everyone else, often with intent.
最初 refers strictly to the beginning of a time sequence, whereas 第一 can also mean first in rank or importance.
最初 means 'the first/beginning', the direct opposite of 最終的 which points to the final stage or outcome.
original activity identifier