Usage patterns
〈人〉を不快にさせるto make someone feel displeased or uncomfortable
His rude attitude made the people around him feel uncomfortable.
〈場所〉の不快を訴えるto complain of discomfort or indisposition in a part of the body
The patient complained of discomfort in the throat.
不快な〈物〉an unpleasant thing (smell, sound, sensation, etc.)
There is an unpleasant smell in this room.